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cdk2 atp

cdk2 atp

Purines and related heterocycles substituted at C-2 with 4′-sulfamoylanilino and at C-6 with a variety of groups have been synthesized with the aim of achieving selectivity of binding to CDK2 over CDK1. 6-Substituents that favor competitive inhibition at

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cdk2 atp 相關資訊

  • Purines and related heterocycles substituted at C-2 with 4′-sulfamoylanilino and at C-6 wi...
    ... Relationships and Insights into the CDK-2 Selectivity ...
    http://pubs.acs.org
  • ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6 Qiuming Kan, Shigeki Jinn...
    ATP-dependent activation of p21WAF1CIP1-associated Cdk2 by ...
    http://www.pnas.org
  • CDK2 was mutated at Lys33 in the ATP binding site (K33R) or Thr160 (T160A) or when treated...
    Autocatalytic Phosphorylation of CDK2 at the Activating ...
    https://www.researchgate.net
  • Cyclin E/CDK2-mediated phosphorylation of NPAT at G1-S transition and until prophase stimu...
    CDK2 - Cyclin-dependent kinase 2 - Homo sapiens (Human) - CD ...
    http://www.uniprot.org
  • CDK2 protects podocytes from apoptosis and reduced expression of CDK2 associates with the ...
    CDK2 cyclin dependent kinase 2 [ (human)]
    https://www.ncbi.nlm.nih.gov
  • dependent phosphorylation of p21 regulates the role of Cdk2 in cisplatin cytotoxicity. Am ...
    Cdk2-dependent phosphorylation of p21 regulates the role of ...
    http://ajprenal.physiology.org
  • Cyclin E-CDK2 is a regulator of p27 Kip1 Robert J. Sheaff, 1 Mark Groudine, 1'4 Matthe...
    Cyclin E-CDK2 is a regulator of p27 Kip1 - Genes & ...
    http://genesdev.cshlp.org
  • The structure of human Cdk2 revealed that CDKs have a modified ATP-binding site that can b...
    Cyclin-dependent kinase - Wikipedia
    https://en.wikipedia.org
  • Cyclin-dependent kinase 2, also known as cell division protein kinase 2, is an enzyme that...
    Cyclin-dependent kinase 2 - Wikipedia
    https://en.wikipedia.org
  • Ninomiya-Tsuji et al. (1991) cloned 2 different cDNAs that can complement cdc28 mutations ...
    OMIM Entry - * 116953 - CYCLIN-DEPENDENT KINASE 2; CDK2
    http://www.omim.org